Analysis of the microRNA (miRNA) signature risk score is illustrated for the five subtypes of GBM. (A) Classical subtype; (B) Neural subtype; (C) Mesenchymal subtype; (D) Proneural-G-CIMP subtype; (E) Proneural-non G-CIMP subtype. (Top) Patient survival status and duration; (Middle) miRNA signature risk score distribution; (Bottom) heat map of ten miRNA expression profiles of patients with glioblastoma multiforme. The rows represent risky and protective miRNAs, and the columns represent patients. The vertical line represents the miRNA signature cutoff dividing patients into low-risk and high-risk groups.