Table 1 Comparison of clinicopathological parameters in women who received radiation stratified by EZH2 expression
Prognostic factors | EZH2 negative | EZH2 positive | |||
|---|---|---|---|---|---|
Number of patients | Percent | Number of patients | Percent | P value | |
Age of diagnosis (N = 62) | |||||
≥ 45 | 11 | 68.75 | 29 | 63.04 | 0.77 |
< 45 | 5 | 31.25 | 17 | 39.96 | |
Race (N = 59) | |||||
Non-Hispanic White | 15 | 93.75 | 33 | 76.74 | 0.26 |
All others | 1 | 6.25 | 10 | 23.26 | |
Lymph node status (N = 60) | |||||
Negative | 3 | 18.75 | 4 | 9.09 | 0.23 |
Positive | 13 | 81.25 | 40 | 90.91 | |
Histologic type (N = 62) | |||||
Ductal | 12 | 75.0 | 42 | 91.30 | 0.19 |
Others | 4 | 25.0 | 4 | 8.70 | |
Lymphovascular invasion (N = 56) | |||||
No | 4 | 26.67 | 5 | 12.20 | 0.23 |
Yes | 11 | 73.33 | 36 | 87.80 | |
ER expression (N = 61) | |||||
Negative | 1 | 6.67 | 33 | 71.74 | < 0.0001 |
Positive | 14 | 93.33 | 13 | 28.26 | |
PR expression (N = 61) | |||||
Negative | 8 | 53.33 | 34 | 73.91 | 0.19 |
Positive | 7 | 46.67 | 12 | 26.09 | |
HER2 expression (N = 61) | |||||
Negative | 11 | 73.33 | 28 | 60.87 | 0.54 |
Positive | 4 | 26.67 | 18 | 39.13 | |
Triple-negative status (N = 61) | |||||
No | 15 | 100.00 | 30 | 65.22 | 0.005 |
Yes | 0 | 0.00 | 16 | 34.78 | |
Radiation type (N = 62) | |||||
Preoperative | 1 | 6.25 | 6 | 13.04 | 0.66 |
Postoperative | 15 | 93.75 | 40 | 86.96 | |
BID radiation (N = 48) | |||||
No | 0 | 0.00 | 10 | 26.32 | 0.09 |
Yes | 10 | 100.00 | 28 | 73.68 | |
Radiation dose (N = 48) | Dose | Dose | |||
11 | 67.09 | 37 | 63.47 | 0.03 | |