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Figure 9 | Journal of Experimental & Clinical Cancer Research

Figure 9

From: Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment

Figure 9

Effects of HDAC8 knockdown and HDAC8 inhibitor treatment on cell cycle distribution. Changes in cell cycle distribution and amount of apoptotic cells (as sub-G1 fraction) after (A) siRNA mediated HDAC8 knockdown (72 h) and (B) HDAC8 inhibitor treatment (compound 2, compound 5, compound 6; IC50, 72 h) were measured by cell cycle analysis using flow cytometry. DMSO served as a solvent control. The relative distribution of the fractions is displayed on the y-axis.

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