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Table 1 Clinicopathologic features of high-grade serous carcinoma with and without STICHGSC: high-grade serous carcinoma; STIC: serous tubal intraepithelial carcinoma

From: IMP3 as a cytoplasmic biomarker for early serous tubal carcinogenesis

  HGSC w/ STIC (n = 48) HGSC w/o STIC (n = 62) P
  No. (%) patients
Age (y) mean ± SD 57.2 ± 2.78 67.1 ± 2.32 < 0.005
40 4 2  
41-50 9 6  
51-60 18 11  
61-70 10 22  
> 70 7 21  
STIC locations    
Left tube 12   
Right tube 29   
Bilateral tubes 7   
Invasive locations^    
Left 3 4  
Right 5 6  
Bilateral 37 52 > 0.05
Cancer size (cm) mean ± SD    
Fallopian tube 0.55 ± 0.21 2.66 ± 0.72 < 0.05
Ovary 3.42 ± 0.52 4.35 ± 0.64 > 0.05
Stage    
I 4 0 < 0.05
II 5 3 > 0.05
III 39 51 > 0.05
IV 0 8 < 0.05
Breast cancer history 8 7  
Family history 12 12  
Prophylactic BSO 5 0  
  1. ^indicating the adnexal location of those invasive cancers. Among the 48 STIC patients, 3 showed STIC only without invasive component. w/: with; w/o: without.
  2. For those cases without gross lesions in the fallopian tube, the lesion size was measured microscopically.