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Table 4 Multivariate analyses of the recurrence-free survival (RFS) and overall survival (OS) in 314 HCC patients stratified by PLAG1 status

From: Pleomorphic adenoma gene 1 mediates the role of karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma

Variate RFS OS
HR (95% CI) P value HR (95% CI) P value
Tumor size, >5 cm 1.061 (1.019-1.105) 0.004 1.081 (1.037-1.128) 0.000
Vascular invasion 1.379 (1.005-1.893) 0.046 1.386 (0.965-1.989) 0.077
HBe antigen positive -- - 1.543 (1.068-2.229) 0.021
No. tumor: multiple 1.444 (1.108-1.880) 0.006 1.484 (1.141-1.930) 0.003
PLAG1 Positive 1.766 (1.315-2.371) 0.000 1.589 (1.138-2.220) 0.007
Edmondson Grade, III + IV 1.139 (0.652-1.987) 0.648 0.953 (0.507-1.791) 0.882
  1. Variates significant in Univariate analyses were applied here.
  2. HR, Hazard ratio; CI, Confidence interval.