Skip to main content
Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention

Figure 1

Amino acid sequences: human and mouse. This figure provides the human Snail1 amino acid sequence. The second representation of the sequence has important features such as phosphorylation sites and zinc fingers highlighted in various colors. 1) Purple indicates nuclear localization signals 2) blue is motif 1 for GSK-3β-mediated phosphorylation 3) green is motif 2 for GSK-3β-mediated phosphorylation 4) yellow is the PAK1 phosphorylation site and 5) gray denotes the zinc-finger region. In addition, human Snail2 (Slug) and mouse Snail1 amino acid sequences are shown for comparison to the human Snail1 sequence. Human Slug is 48% identical to human Snail1, and mouse Snail1 is 88% identical to human Snail1. The sequence alignments were run through BLAST [9].

Back to article page