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Table 1 Clinical characteristics and peri-operative data of patients with prostate cancer who underwent surgery with TIVA-TCI or BAL anaesthesia

From: Perioperative changes in pro and anticoagulant factors in prostate cancer patients undergoing laparoscopic and robotic radical prostatectomy with different anaesthetic techniques

  TIVA-TCI (n. 54) BAL (n. 48) P
Clinical data    
Age (yrs) 60.66 (5.91) 62.16 (6.23) 0.31
Venous thromboembolism risk    
Highest risk 54 (100%) 48 (100%) 1
Prostate cancer risk*    
Intermediate-risk 26 (48.1%) 30 (62.5%)  
High-risk 28 (51.8%) 18 (37.5%) 0.17
ASA, n (%):    
I 4 (7.4%) 6 (12.5%)  
II 50 (92.6%) 42 (87.5%) 0.39
Histological grade of cancer    
G2 (Gleason 5–6) 15 (27.8%) 14 (29.2)  
G3 (Gleason 7–10) 39 (72.2%) 34 (70.8%) 0.88
pT, n (%)    
2 30 (55.6%) 32 (66.7%) 0.25
3 24 (44.4%) 16 (33.3%)  
pN, n (%) #    
0 17 (85.0%) 24 (96.0%) 0.20
1 3 (15.0%) 1 (4.0%)  
Peri-operative data    
Type of surgery    
LRP 36 (66.7%) 34 (70.8%) 0.65
RALP 18 (33.3%) 14 (29.2%)  
Time of anaesthesia (min) 107.5 (16.8) 101.4 (26.2) 0.26
Blood loss (ml) 123.3 (131.1) 121.4 (110.6) 0.81
Total amount of crystalloid received (ml) 468.5 (110.21) 496.8 (198.5) 0.27
Intra-operative body temperature 36.2 (0.3) 36.1 (0.2) 0.83
Intra-operative MAP (mmHg) 104.6 (10.5) 106.2 (10.2) 0.61
Intra-operative SpO2 (%) 96.7 (0.9) 97.8 (1.8) 0.75
Arterial lactate level (mmol/l)    
1 h post-surgery 0.7 (0.2) 0.6 (0.4) 0.32
24 h post-sugery 1.7 (0.2) 1.8 (0.2) 0.82
Intra-operative BE (mmol/l) 0.3 (0.4) 0.4 (0.4) 0.62
Intra-operative PaO2 (mmHg) 219.4 (11.2) 216.5 (16.8) 0.72
  1. Values are expressed in absolute values or mean (SD).
  2. Abbreviations: TIVA-TCI total intravenous anaesthesia with target-controlled infusion, BAL balanced inhalation anaesthesia, LRP conventional laparoscopic radical prostatectomy, RALP robot-assisted laparoscopic prostatectomy.
  3. *According to Guidelines on Prostate Cancer, European Association of Urology, 2012.
  4. #Lymph node dissection was made in 45 out of 102 pts.