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Table 2 Clinical characteristics and peri-operative data of patients with prostate cancer, divided in 4 subgroups according type of anesthesia and surgery

From: Perioperative changes in pro and anticoagulant factors in prostate cancer patients undergoing laparoscopic and robotic radical prostatectomy with different anaesthetic techniques

  TIVA-TCI LRP (n. 36 pts) TIVA-TCI RALP (n. 18 pts) BAL LRP (n. 34 pts) BAL RALP (n. 14 pts) P
Clinical data      
Age (yrs) 61.4 (5.7) 59.5 (6.7) 63.2 (5.8) 60.1 (7.7) 0.25
ASA, n (%):      
I 3 (8.3%) 1 (5.6%) 5 (14.7%) 1 (7.1%) 0.68
II 33 (91.7%) 17 (94.4%) 29 (85.3%) 13 (92.9%)  
Histological grade of cancer      
G2 (Gleason 5–6) 9 (25.0%) 6 (33.3%) 10 (29.4) 4 (28.6) 0.93
G3 (Gleason 7–10) 27 (75.0%) 12 (66.7%) 24 (70.6%) 10 (71.4%)  
pT, n (%)      
2 12 (33.3%) 18 (100%) 18 (52.9%) 14 (100%) 0.001
3 24 (66.7%) 0 16 (47.1%) 0  
pN, n (%)*      
0 11 (84.6%) 6 (85.7%) 14 (93.3%) 10 (100%) 0.57
1 2 (15.4%) 1 (14.3%) 1 (6.7%) 0  
Perioperative data      
Time of anaesthesia (min) 104.0 (21.3) 109.7 (24.4) 98.8 (30.2) 105.2 (24.8) 0.32
Blood loss (ml) 119.2 (140.3) 128.3 (150.1) 118.2 (121.4) 125.2 (131.5) 0.30
Total amount of crystalloid received (ml) 475.4 (100.4) 460.8 (118.4) 486.1 (166.4) 499.8 (200.2) 0.21
Intra-operative body temperature 36.2 (0.3) 36.1 (0.4) 36.1 (0.2) 36.1 (0.3) 0.87
Intra-operative MAP (mmHg) 103.8 (11.8) 105.3 (12.5) 105.4 (12.4) 106.8 (12.2) 0.54
Intra-operative SpO2 (%) 96.7 (0.9) 96.7 (0.9) 97.8 (1.8) 97.8 (1.8) 0.75
Arterial lactate level (mmol/l)      
1 h post-surgery 0.7 (0.2) 0.7 (0.3) 0.6 (0.3) 0.6 (0.4) 0.81
24 h post-sugery 1.8 (0.3) 1.7 (0.2) 1.7 (0.3) 1.8 (0.3) 0.77
Intra-operative BE (mmol/l) 0.3 (0.4) 0.4 (0.3) 0.3 (0.4) 0.4 (0.3) 0.78
Intra-operative PaO2 (mmHg) 220.6 (13.2) 218.8 (13.4) 214.6 (18.6) 219.5 (19.0) 0.22
  1. Values are expressed in absolute values or mean (SD).
  2. Abbreviations: TIVA-TCI total intravenous anaesthesia with target-controlled infusion, BAL balanced inhalation anaesthesia, LRP laparoscopic radical prostatectomy, RALP robot-assisted laparoscopic prostatectomy.
  3. *Lymph node dissection was made in 45 out of 102 pts.