Figure 3

IHC staining of FHIT protein in adenoma samples. A) High cytoplasmic staining in 85% of colonic glands (grade 3+), a small fraction of glands (15%-20%) showing low intensity staining (grade 2+). Magnification 2.5 ×. B) High cytoplasmic staining in 85% of colonic glands (grade 3+). Magnification 20×. C) Medium cytoplasm staining in 80% of colonic glands (grade 2+). Magnification 20×. D) Low cytoplasmic staining in 60% of colonic glands; 40%, grade 1+ and 20%, grade 2+. Magnification 2.5×. E) Negative cytoplasmic staining of colonic glands. Magnification 2.5 x.