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Table 1 Association between expression level of DPYSL3 mRNA and clinicopathological parameters in 238 patients

From: Dihydropyrimidinase-like 3 facilitates malignant behavior of gastric cancer

Variables

HighDPYSL3mRNA in GC tissue (n)

LowDPYSL3mRNA in GC tissue (n)

P-value

Age

  

0.793

< 65 year

51

49

≥ 65 year

68

70

Gender

  

0.453

Male

87

92

Female

32

27

Carcinoembryonic antigen (ng/ml)

  

0.415

≤ 5

93

98

> 5

26

21

Carbohydrate antigen 19–9 (IU/ml)

  

0.504

≤ 37

95

99

> 37

24

20

Tumor location

  

0.769

Entire

12

8

Upper third

24

27

Middle third

37

35

Lower third

46

49

Tumor size (mm)

  

0.090

< 50

48

61

≥ 50

71

58

Tumor depth (UICC)

  

<0.001*

pT1-3

51

77

pT4

68

42

Histology

  

0.098

Papillary

1

1

Well differentiated

4

10

Moderately differentiated

33

48

Poorly differentiated

74

56

Signet ring cell

5

2

Mucinous

2

2

Differentiation

  

0.006*

Differentiated

39

60

Undifferentiated

80

59

Lymphatic involvement

  

0.016*

Absent

11

24

Present

108

95

Vessel invasion

  

0.036*

Absent

44

60

Present

75

59

Infiltrative growth type

  

<0.001*

Invasive growth

55

28

Expansive growth

64

90

Lymph node metastasis

  

<0.001*

Absent

32

57

Present

87

62

Peritoneal lavage cytology

  

0.001*

Negative

84

104

Positive

35

15

UICC stage

  

0.032*

I - III

77

92

IV

42

27

  1. Abbreviations: UICC Union for International Cancer Control. *Statistically significant (P < 0.05).