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Table 2 Relationship between PCDH8 methylation and clinicopathological characteristics in NMIBC (n = 233)

From: Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer

Features

Variables

No.

M (%)

U (%)

P

Age

65

86

46(53.5)

40(46.5)

0.7342

>65

147

82(55.8)

65(44.2)

 

Sex

Male

161

94(58.4)

67(41.6)

0.1135

Female

72

34(47.2)

38(52.8)

 

Number

Single

142

82(57.8)

60(42.2)

0.2814

Multiple

91

46(50.6)

45(49.4)

 

Size

≤3 cm

139

69(49.6)

70(50.4)

0.0482

>3 cm

94

59(62.8)

35(37.2)

 

Grade

G1/ G2

144

67(46.5)

77(53.5)

0.0010

G3

89

61(68.5)

28(31.5)

 

Stage

Ta

95

43(45.3)

52(54.7)

0.0138

T1

138

85(61.6)

53(38.4)

 

Recurrence

No

127

40(31.5)

87(68.5)

<0.0001

Yes

106

88(83.0)

18(17.0)

 

Progression

No

175

80(45.7)

95(54.3)

<0.0001

Yes

58

48(82.8)

10(17.2)

 
  1. M: Methylation; U: Unmethylation.