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Table 3 The predictive value of PCDH8 methylation for the recurrence-free survival in non muscle invasive bladder cancer (n = 233)

From: Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P

HR

95% CI

P

PCDH8 methylation (M vs. U)

7.083

2.576-14.621

<0.0001

4.739

1.872-12.053

<0.0001

Age (>65 vs. ≦65)

1.241

0.768-5.724

0.7931

   

Sex (Male vs. Female)

0.926

0.753-3.761

0.8541

   

Number (Multiple vs. Single)

1.411

0.674-12.653

0.7244

   

Size (>3 cm vs. ≤3 cm)

1.537

0.687-10.431

0.7196

   

Grade (G3 vs. G1/G2)

5.067

1.933-10.763

0.0006

2.055

1.644-8.431

0.0137

Stage (T1 vs. Ta)

2.073

1.027-9.754

0.0176

1.371

0.824-6.084

0.0735

  1. HR: Hazard Ratio; M: Methylated; U: unmethylated.