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Table 4 The predictive value of PCDH8 methylation for the progression-free survival in non muscle invasive bladder cancer (n = 233)

From: Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P

HR

95% CI

P

PCDH8 methylation (M vs. U)

4.893

1.872-9.433

<0.0001

2.523

1.654-7.431

0.0036

Age (>65 vs. ≦65)

0.896

0.873-5.215

0.8614

   

Sex (Male vs. Female)

1.213

0.855-5.217

0.5461

   

Number (Multiple vs. Single)

1.322

0.729-8.537

0.4668

   

Size (>3 cm vs. ≤3 cm)

1.227

0.579-11.460

0.4962

   

Grade (G3 vs. G1 / G2)

3.679

1.463-7.754

0.0017

1.874

1.237-6.873

0.0233

Stage (T1 vs. Ta)

1.625

0.893-6.792

0.0614

   
  1. HR: Hazard Ratio; M: Methylated; U: Unmethylated.