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Figure 6 | Journal of Experimental & Clinical Cancer Research

Figure 6

From: MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6

Figure 6

Knock-down of CDK6 phenocopied the effect of miR-320c. (A, B) The knock-down of CDK6 via RNAi technique reduced the expression of CDK6 (levels of mRNA and protein). (C) SiCDK6 suppressed bladder cancer cell growth. (D) SiCDK6 reduced the colony formation rate in both cell lines (representative wells were presented). (E) SiCDK6 induced G1-phase arrest in both cell lines (representative histograms were presented). (F) SiCDK6 yield an inhibitory effect on invasion and migration in both cell lines (×200) (*P < 0.05).

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