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Figure 5 | Journal of Experimental & Clinical Cancer Research

Figure 5

From: Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion

Figure 5

LKB1 was localized at adheren junctions and regulated the expressions of EMT markers. (A) MCF-10A was stained for LKB1 (green), E-cadherin (red) and DAPI (blue). (B) Expressions of EMT markers in control and LKB1 overexpressing MDA-MB-435 s. (C) MCF-7 cells were transfected with non-targeting siRNA (NT) or siLKB1(1342/1972). The protein levels of E-cadherin, N-cadherin and α-SMA were determined by western blot.

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