Figure 2

Targeted microarray result demonstrating a partial deletion of exon 10 in MSH2 at the A) gene level and B) probe level. Vertical yellow lines represent MSH2 exons. Individual probes are represented by the black dots. Probe clusters for exons devoid of LRs are shown to center at the 0 horizontal line, which represents two allelic copies. The cluster of microarray probes spanning the 5’ portion of MSH2 exon 10 probe centers at approximately −0.75, indicating the presence of a partial deletion of this exon.