|
Age (years)
| | | | | | |
|
Median
|
64
| |
60
| |
62
| |
|
Range
|
38-88
| |
38-81
| |
38-77
| |
|
Smoking history
| | | | | | |
|
Never smokers
|
63
|
61
|
40
|
60
|
27
|
69
|
|
Former smokers
|
8
|
8
|
5
|
8
|
4
|
10
|
|
Current smokers
|
32
|
31
|
21
|
32
|
8
|
21
|
|
Stage
| | | | | | |
|
IIIB
|
30
|
29
|
17
|
26
|
11
|
28
|
|
IV
|
73
|
71
|
49
|
74
|
28
|
72
|
|
Number of sites of metastases
| | | | | | |
|
1
|
16
|
16
|
18
|
27
|
9
|
23
|
|
2
|
25
|
24
|
26
|
39
|
13
|
33
|
|
≥3
|
62
|
60
|
22
|
34
|
17
|
44
|
|
CNS metastases
| | | | | | |
|
Yes
|
14
|
14
|
12
|
18
|
7
|
18
|
|
No
|
89
|
86
|
54
|
82
|
32
|
82
|
|
Previous surgery on primary
| | | | | | |
|
Yes
|
46
|
45
|
20
|
30
|
14
|
36
|
|
No
|
57
|
55
|
46
|
70
|
25
|
64
|
|
Previous (neo-)adjuvant CT
| | | | | | |
|
Yes
|
9
|
9
|
5
|
8
|
4
|
10
|
|
No
|
94
|
91
|
61
|
92
|
35
|
90
|
|
Previous adjuvant RT
| | | | | | |
|
Yes
|
4
|
4
|
2
|
4
|
3
|
8
|
|
No
|
99
|
96
|
63
|
96
|
36
|
92
|
|
First-line CT regimen
| | | | | | |
|
Platinum + Paclitaxel
|
10
|
10
|
10
|
15
|
5
|
13
|
|
Platinum + Gemcitabine
|
39
|
39
|
39
|
59
|
21
|
54
|
|
Platinum + Pemetrexed
|
13
|
13
|
13
|
20
|
6
|
15
|
|
Cisplatin + Vinorelbine
|
2
|
2
|
2
|
3
|
1
|
3
|
|
Cisplatin-based triplet CT
|
2
|
2
|
2
|
3
|
2
|
5
|
|
Single-agent CT*
|
26
|
26
|
-
|
-
|
4
|
10
|
|
Best supportive care only
|
8
|
8
|
-
|
-
|
-
|
-
|
|
Anti-EGFR TKI treatment line
| | | | | | |
|
2
|
28
|
27
|
24
|
36
|
27
|
69
|
|
≥3
|
12
|
12
|
9
|
14
|
12
|
31
|
