| Correlative cohort (n = 66) | Anti-EGFR treated (n = 39) | ||
---|---|---|---|---|
 | Median | p | Median | p |
Smoking history | Â | 0.246 | Â | 0.238 |
  Never smokers | 5.0 |  | 3.2 |  |
  Former smokers | 5.0 |  | 5.6 |  |
  Current smokers | 7.0 |  | 10.0 |  |
Stage | Â | 0.130 | Â | 0.423 |
  IIIB | 7.6 |  | 11.4 |  |
  IV | 5.0 |  | 4.8 |  |
Age | Â | 0.233 | Â | 0.894 |
<70 years | 5.5 | Â | 7.2 | Â |
70years | 6.5 | Â | 5.0 | Â |
EGFR mutation* | Â | 0.373 | Â | 0.052 |
  Exon 19 mutation | 4.4 |  | 12.7 |  |
  Exon 20 mutation | 8.0 |  | NA |  |
  Exon 21 mutation | 3.2 |  | 1.4 |  |