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Table 1 Characteristics of the cancer sera and types of cell lines cultured

From: Transfer of malignant trait to immortalized human cells following exposure to human cancer serum

Cells/Conditions Animals with tumora Latency (days) Tumor volume (cm3)
HEK293/Control human serum 0/6 30 --
HEK293/Case18 (PcC/LM) 3/3 30 0.930 +/− 0.130
HEK293 /Case21 (Leiomyosarcoma) 3/3 30 0.610 +/− 0.122
HEK293/Case9 (CRC/LM) 3/3 30 0.241 +/− 0.090
HEK293/Case14 (BC/LM) 3/3 30 1.064 +/− 0.073
HEK293/Control medium 0/3 30 --
HEK293/CM-Colo320 3/3 30 0.288 +/− 0.017
hESC WA01/Control human serum 0/2 185 --
hESC WA01/Case23 (CC/LM) 0/2 185 --
hESC WA01/Control human serum 0/5 210 --
hESC WA01/Case4 (GC/Peritoneal seeding) 0/5 210 --
hESC WA01/Control human serum 0/5 120 --
hESC WA01/Case8 (CC/LM) 0/6 120 --
hESC WA01/Control human serum 0/4 155 --
hESC WA01/Case19 (GC/LM) 0/7 155 --
hESC WA01/Control human serum 0/2 119 --
hESC WA01/Case7 (Neuroendocrine) 0/3 119 --
hESC WA01/Control human serum 0/2 104 --
hESC WA01/Case10 (BC/BM + lM) 0/2 104 --
hESC WA01/Control human serum 0/3 60 --
hESC WA01/Case13 (CRC/LM + BM) 0/3 60 --
hALF/Control human serum 0/2 70 --
hALF/Case16 (CRC/LM) 0/2 70 --
hMSC /Control human serum 0/2 98 --
hMSC /Case20 (CC/LM) 0/2 98 --
hMSC /Case22 (BrC/LM + lM) 0/2 98 --
  1. Target cells were exposed for 3 weeks to cancer patient sera or Colo-320 cell line conditioned medium. Cells were inoculated subcutaneously to immunodepressed mice and mice were monitored for tumor growth.
  2. athis ratio represent the number of mice that develop subcutaneous tumour over the total number of injected mice per cell culture condition.
  3. BC; Breast cancer, BM; Bone metastasis, CC; Colon cancer, CRC; Colorectal cancer, GC; Gastric cancer, hESC; Human embryonic stem cells, hALF; Human adult liver fibroblasts, hMSC; Human mesenchymal stem cells, LM; Liver metastasis, lM; Lung metastasis, PcC; Pancreatic cancer.