Decreased expression of prenyl diphosphate synthase subunit 2 correlates with reduced survival of patients with gastric cancer

Table 1 Association between expression level of PDSS2 mRNA and clinicopathological parameters of 238 patients

Variables	DecreasedPDSS2mRNA in GC tissues (n)	Others (n)	Pvalue
Age			0.408
< 65 year	29	71
≥ 65 year	47	91
Gender			0.551
Male	59	120
Female	17	42
Subtype			0.298
Proximal nondiffuse	22	32
Diffuse	14	33
Distal nondiffuse	40	96
Carcinoembryonic antigen (ng/ml)			0.490
≤ 5	59	132
> 5	17	30
Carbohydrate antigen 19-9 (IU/ml)			0.015*
≤ 37	55	139
> 37	21	23
Tumor size (mm)			0.104
< 50	29	80
≤ 50	47	82
Tumor depth (UICC)			0.419
pT1	14	32
pT2	6	24
pT3	19	33
pT4	37	73
Differentiation			0.217
Differentiated	36	63
Undifferentiated	40	99
Lymphatic involvement			0.201
Absent	8	27
Present	68	135
Vessel invasion			0.535
Absent	31	73
Present	45	89
Infiltrative growth type			0.443
Invasive growth	24	59
Expansive growth	52	102
Lymph node metastasis (UICC)			0.022*
pN0	19	70
pN1	8	19
pN2	12	24
pN3	37	49
Peritoneal lavage cytology			0.306
Negative	57	131
Positive	19	31
Distant metastasis (UICC)			0.228
M0	50	119
M1	26	43

*Statistically significant (P <0.05). GC, gastric cancer; UICC, Union for International Cancer Control.

ISSN: 1756-9966