Figure 1
From: Progress in oncolytic virotherapy for the treatment of thyroid malignant neoplasm
TSHR localization and structure. (A) Thyroid follicle, where the TSH-stimulated synthesis of thyroid hormone occurs following iodide uptake and organification into thyroglobulin. (B) TSHR protein structure, showing the β subunit composed of leucine-rich repeats and the N-terminus, and the β subunit composed of 7 trans-membrane domains, the intra-cellular and extra-cellular loops and the C-terminus. Figure adapted with permission from Atlas Genet Cytogenet Oncol Haematol [103].