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Table 1 Bromelain and NAC concentrations used in single agent and combination treatment of gastrointestinal carcinoma cells

From: Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: significance of combination therapy

Cell line Single agent Bromelain (?g/mL) Single agent NAC (mM) Combinations (Bromelain/NAC)
MKN45 10 25 50 100 200 400 600 1 5 10 25 50 75 - 50/1 50/5 50/10 75/1 75/5 75/10 100/1 100/5 100/10
KATO-III 10 50 75 100 200 300 400 1 5 10 25 50 75 100 50/1 50/5 50/10 100/1 100/5 100/10 200/1 200/5 200/10
HT29-5F12 5 10 20 40 50 - - 1 5 10 25 50 75 - 5/1 5/5 5/10 10/1 10/5 10/10 20/1 20/5 20/10
HT29-5M21 5 10 20 40 50 - - 1 5 10 25 50 75 - 5/1 5/5 5/10 10/1 10/5 10/10 20/1 20/5 20/10
LS174T 10 20 30 40 50 - - 2.5 5 10 20 30 40 - 10/5 10/10 10/20 20/5 20/10 20/20 30/5 30/10 30/20