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Table 1 Bromelain and NAC concentrations used in single agent and combination treatment of gastrointestinal carcinoma cells

From: Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: significance of combination therapy

Cell line

Single agent Bromelain (?g/mL)

Single agent NAC (mM)

Combinations (Bromelain/NAC)

MKN45

10

25

50

100

200

400

600

1

5

10

25

50

75

-

50/1

50/5

50/10

75/1

75/5

75/10

100/1

100/5

100/10

KATO-III

10

50

75

100

200

300

400

1

5

10

25

50

75

100

50/1

50/5

50/10

100/1

100/5

100/10

200/1

200/5

200/10

HT29-5F12

5

10

20

40

50

-

-

1

5

10

25

50

75

-

5/1

5/5

5/10

10/1

10/5

10/10

20/1

20/5

20/10

HT29-5M21

5

10

20

40

50

-

-

1

5

10

25

50

75

-

5/1

5/5

5/10

10/1

10/5

10/10

20/1

20/5

20/10

LS174T

10

20

30

40

50

-

-

2.5

5

10

20

30

40

-

10/5

10/10

10/20

20/5

20/10

20/20

30/5

30/10

30/20