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Table 2 Expression of CXCR4 in human intrahepatic cholangiocarcinomas and lymph node metastasis

From: Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway

  Case n CXCR4 expression Pvalue
High Low
n(%) n(%)
Primary intrahepatic cholangiocarcinomas 122    
 With nodal metastases 75 50 (66.7) 25(33.3) <0.001
 Without nodal metastasis 47 10 (21.3) 37(78.7)  
Intrahepatic carcinomas with nodal metastasis     
 Primary IHCC 75 50(66.7) 25(33.3) 0.038
 Matched lymph node metastases 75 62(82.7) 13(17.3)