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Table 1 Correlation between Wnt3a and clinicopathologic characteristics of patients with colon cancer

From: Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression

Viariant Total Wnt3a expression χ2 PValue
Negative (%) Weak expression (%) Strong expression (%)
Age       
  <45 27 2 (7.4) 17 (63) 8 (29.6) 1.340 0.512
  ≥45 176 22 (12.5) 117 (66.5) 37 (21.0)   
Sex       
  Male 95 10 (10.5) 68 (71.6) 17 (17.9) 2.563 0.278
  Female 108 14 (13) 66 (61.1) 28 (25.9)   
Tumor size       
  ≥5 cm 166 6 (9.1) 41 (62.1) 19 (28.8) 2.775 0.250
  <5 cm 137 18 (13.1) 93 (67.9) 26 (19.0)   
Histological differentiation       
  Well differentiated 16 5 (31.2) 10 (62.5) 1 (6.2) 15.127 0.004*
  Moderately differentiated 101 11 (10.9) 74 (73.3) 16 (15.8)   
  Poorly differantiated 86 8 (9.3) 50 (58.1) 28 (32.6)   
Clinical stage       
  TNMI 10 5 (50.0) 4 (40.0) 1 (10.0) 17.456 0.008*
  TNMII 128 15 (11.7) 86 (67.2) 27 (21.1)   
  TNMIII 54 4 (7.4) 37 (68.5) 13 (24.1)   
  TNMIV 11 0 (0.0) 7 (63.6) 4 (36.4)   
Metastasis/recurrence       
  Absent 135 20 (14.8) 91 (67.4) 24 (17.8) 6.674 0.036*
  Present 68 4 (5.9) 43 (63.2) 21 (30.9)   
  1. *Significantly different.