Table 1 Correlation between Wnt3a and clinicopathologic characteristics of patients with colon cancer
Viariant | Total | Wnt3a expression | χ2 | PValue | ||
|---|---|---|---|---|---|---|
Negative (%) | Weak expression (%) | Strong expression (%) | ||||
Age | ||||||
<45 | 27 | 2 (7.4) | 17 (63) | 8 (29.6) | 1.340 | 0.512 |
≥45 | 176 | 22 (12.5) | 117 (66.5) | 37 (21.0) | ||
Sex | ||||||
Male | 95 | 10 (10.5) | 68 (71.6) | 17 (17.9) | 2.563 | 0.278 |
Female | 108 | 14 (13) | 66 (61.1) | 28 (25.9) | ||
Tumor size | ||||||
≥5 cm | 166 | 6 (9.1) | 41 (62.1) | 19 (28.8) | 2.775 | 0.250 |
<5 cm | 137 | 18 (13.1) | 93 (67.9) | 26 (19.0) | ||
Histological differentiation | ||||||
Well differentiated | 16 | 5 (31.2) | 10 (62.5) | 1 (6.2) | 15.127 | 0.004* |
Moderately differentiated | 101 | 11 (10.9) | 74 (73.3) | 16 (15.8) | ||
Poorly differantiated | 86 | 8 (9.3) | 50 (58.1) | 28 (32.6) | ||
Clinical stage | ||||||
TNMI | 10 | 5 (50.0) | 4 (40.0) | 1 (10.0) | 17.456 | 0.008* |
TNMII | 128 | 15 (11.7) | 86 (67.2) | 27 (21.1) | ||
TNMIII | 54 | 4 (7.4) | 37 (68.5) | 13 (24.1) | ||
TNMIV | 11 | 0 (0.0) | 7 (63.6) | 4 (36.4) | ||
Metastasis/recurrence | ||||||
Absent | 135 | 20 (14.8) | 91 (67.4) | 24 (17.8) | 6.674 | 0.036* |
Present | 68 | 4 (5.9) | 43 (63.2) | 21 (30.9) | ||