Figure 5
From: MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer
miR-301a regulated metastasis and invasion through suppressing TGFBR2 in CRC cells. (A) Western bloting showed TGFBR2 was downregulated in SW480 cells transiently transfected with TGFBR2 siRNA. (B) The cell invasion and migration ability were improved in TGFBR2 downregulated SW480 cells. (C) Expression of TGFBR2 protein in SW620/LV-anti-miR-301a or SW620/LV-anti-miR-NC cells transiently transfected with TGFBR2 siRNA or siRNA/NC. (D) Cell invasion and migration assays of SW620/LV-anti-miR-301a or SW620/LV-anti-miR-NC cells transiently transfected with TGFBR2 siRNA or siRNA/NC. Data were representedas means ± SD from 3 independent experiments. **, P < 0.01.