Table 2 Relationship between the Pim-1, RUNX3 level and the clinical characteristics
From: Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma
Variable | Patients (total = 54) | Pim-1 | p-value | RUNX3 | p-value | |||
|---|---|---|---|---|---|---|---|---|
Negative | Positive | Negative | Positive | |||||
Gender | Male | 23 | 4 | 19 | 1.000 | 19 | 4 | 0.741 |
Femal | 31 | 5 | 26 | 24 | 7 | |||
Age | <46 | 26 | 3 | 23 | 0.495 | 21 | 5 | 1.000 |
≥46 | 28 | 6 | 22 | 22 | 6 | |||
T-status | T1-2 | 22 | 8 | 14 | 0.002 | 14 | 8 | 0.036 |
T3-4 | 32 | 1 | 31 | 29 | 3 | |||
Tumor location | Major salivary | 21 | 4 | 17 | 0.723 | 15 | 6 | 0.305 |
Minor salivary | 33 | 5 | 28 | 28 | 5 | |||
Histological type | Cribiform | 24 | 4 | 20 | 1.000 | 22 | 2 | 0.116 |
Tubula | 12 | 2 | 10 | 8 | 4 | |||
Solid | 18 | 3 | 15 | 13 | 5 | |||
Lymph node involvement | Yes | 9 | 0 | 9 | 0.328 | 8 | 1 | 0.667 |
No | 45 | 9 | 36 | 35 | 10 | |||
Nerve invasion | Yes | 0 | 1 | 29 | 0.007 | 28 | 2 | 0.007 |
No | 24 | 8 | 16 | 15 | 9 | |||
Distant metastasis | Yes | 8 | 0 | 8 | 0.326 | 8 | 0 | 0.184 |
No | 46 | 9 | 37 | 35 | 11 | |||