Figure 9
IPA summary of the pathways regulated by EBF3 overexpression in HL-60 cells. Datasets representing 370 key genes involved in apoptosis with altered expression profiles that were obtained from real-time PCR arrays were imported into the IPA Tool and the following data is illustrated: (A) A list of the top five networks with their respective scores obtained from IPA. (B) A list of the top five molecular and cellular functions with their respective scores obtained from IPA. (C) A list of the top five canonical pathways with their respective scores obtained from IPA. (D) The network representation of the most highly rated network is shown. Genes that are shaded were determined to be statistically significant. A solid line represents a direct interaction between the two gene products and a dotted line means an indirect interaction.