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Table 6 Down-regulated genes in HL-60 cells treated with PLVX- EBF3 compared with control group

From: Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia

 

Gene

Description

Vector

EBF3

FC

P

1

ZNF443

zinc finger protein 443

199.493

3.80756

0.019086

0.000602

2

BIRC8

baculoviral IAP repeat containing 8

433.5919

29.62754

0.06833

0.007686

3

BCL2L11

BCL2-like 11 (apoptosis facilitator)

8365.257

663.1

0.079268

0.01033

4

CARD17

caspase recruitment domain family, member 17

28.84389

2.494701

0.08649

0.012285

5

NLRP2

NLR family, pyrin domain containing 2

16.79773

1.462936

0.087091

0.012456

6

NTF3

neurotrophin 3

910.2974

122.6894

0.134779

0.029574

7

INHA

inhibin, alpha

2435.824

404.1836

0.165933

0.044486

8

IL10

interleukin 10

115.3756

24.23243

0.210031

0.007331

9

FADD

Fas (TNFRSF6)-associated via death domain

34164.11

8072.876

0.236297

0.008898

10

CD5

CD5 molecule

233.9723

60.92097

0.260377

0.010608

11

SNCA

synuclein, alpha

38703.97

10360.94

0.267697

0.011798

12

SST

somatostatin

54.95558

15.65842

0.284929

0.015721

13

SERPINB9

serpin peptidase inhibitor, clade B

4153.737

1191.751

0.286911

0.017364

14

PIDD

p53-induced death domain protein

25712.71

7480.23

0.290916

0.0130711

15

TPD52L1

tumor protein D52-like 1

621.7514

187.2558

0.301175

0.013438

16

RARG

retinoic acid receptor, gamma

2628.81

808.3672

0.307503

0.01493

17

ALOX15B

arachidonate 15-lipoxygenase, type B

8365.257

2700.231

0.322791

0.015529

18

PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

657.2025

219.6202

0.334174

0.016946

19

LCK

LCK proto-oncogene, Src family tyrosine kinase

17082.06

5788.071

0.338839

0.017284

20

ADRA1D

adrenoceptor alpha 1D

247.313

91.70109

0.37079

0.024013

21

PCBP4

poly(rC) binding protein 4

9675.993

3587.758

0.37079

0.024013

22

TNFRSF18

tumor necrosis factor receptor superfamily, member 18

3420.98

1340.789

0.391931

0.0225247

23

GRM4

glutamate receptor, metabotropic 4

576.1074

233.7572

0.405753

0.023978

24

CRYAA

crystallin, alpha A

1184.608

490.7576

0.414278

0.024834

25

FASLG

Fas ligand (TNF superfamily, member 6)

233.9723

99.65477

0.425925

0.026701

26

ALOX12

arachidonate 12-lipoxygenase

153.2979

66.31

0.432556

0.026786

27

PEA15

phosphoprotein enriched in astrocytes 15

3083.16

1350.115

0.4379

0.027532

28

S100B

S100 calcium binding protein B

4211.721

1896.163

0.450211

0.028891

29

NLRP3

NLR family, pyrin domain containing 3

16614.95

7797.884

0.469329

0.037943

30

TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

3984.531

1936.005

0.48588

0.036438

31

TNFRSF8

tumor necrosis factor receptor superfamily, member 8

7487.114

3740.115

0.49954

0.034869