Colocalization of FSHR with CD34 and D2-40 in tumor peripheral microvessels. Immunohistochemical analysis was performed on three consecutive paraffin-embedded sections of human invasive breast cancer tissues by using the standard method with peroxidase. Blood vessels (arrows) stained for the endothelial marker CD34 (A) are FSHR+ (B). By contrast, the D2-40-positive lymphatic endothelia (arrowheads) do not express FSHR (C). Scale bars represent 20 μm.