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Table 3 Univariate and multivariate analysis of overall survival

From: Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer

  Univariate analysis Multivariate analysis
  HR (95% CI) P value HR (95% CI) P Value
Age     
 <65 1    
 ≥65 1.350(0.706-2.581) 0.364   
Gender     
 Male 1    
 Female 0.910(0.503-1.648) 0.756   
Location     
 Right 1   1  
 Others 0.470(0.259-0.852) 0.013* 0.501(0.272-0.922) 0.026*
Tumor size (cm)     
  < 5 1    
  ≥ 5 1.801(0.993-3.267) 0.053   
AJCC stage     
 I + II 1   1  
 III + IV 3.106(1.701-5.671) <0.001* 82.935(13.868-495.998) <0.001*
T stage     
 T1 + T2 1    
 T3 + T4 1.662(0.514-5.370) 0.396   
N stage     
 N0 1   1  
 N1 + N2 3.106(1.701-5.671) <0.001* 2.558(1.355-4.828) 0.004*
M stage     
 M0 1   1  
 M1 10.801(2.448-47.658) 0.002* 77.710(13.384-451.213) <0.001*
Differentiation     
 Well + Moderate 1    
 Poor 2.026(0.627-6.548) 0.238   
Vascular invasion     
 No 1   1  
 Yes 6.188(2.093-18.295) <0.001* 1.111(0.246-5.019) 0.892
KIF26B     
 Low 1   1  
 High 5.311(2.360-11.952) <0.001* 5.621(2.302-13.730) <0.001*
Ki67     
 Low 1   1  
 High 2.343(1.254-4.377) 0.008* 1.433(0.718-2.860) 0.307
  1. *indicates P<0.05.