Figure 1

Icaritin exhibits cytotoxicity on ENKL cells. A. The chemical structure of Icaritin. B. Effects of Icaritin on SNK-10 and SNT-8 cell viability by the CCK-8 assay. (a) IC₅₀ curves after 72 h treatment (n = 3); (b) Time- and dose–response curves (n = 3). C. Effects of Icaritin on SNK-10 and SNT-8 cell proliferation. Cell proliferation was determined by the CFDA-SE assay after 48 h treatment. (a) CFDA-SE flow cytometry histograms; (b) The mean cellular florescence intensity (MFI) (n = 3). *p < 0.05, ^#p < 0.01 vs control.