Figure 1
HCS prohibited bladder cancer cells growth and induced apoptosis of T24 and EJ cells. (A) Effect of HCS on proliferation of T24, EJ, RT-4, and SV-HUC-1 cells. Values are given as a percentage of untreated control cells. The data are presented as the average for triplet results from a representative experiment; bars, SD. (B) The ultrastructural morphologic changes of the T24 cells treated with HCS (1:100) under the transmission electron microscope. (C) The apoptotic fraction of cells detected by annexin V staining (x-axis)/propidium iodide staining (y-axis) after HCS treatments and the percentages showing the annexin V-positive/PI-negative fraction. Columns are expressed as mean ± SD of 3 independent experiments. *, p < 0.05 for HCS vs. control.