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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge

Figure 1

CCAT1 expression in HCC and its association with patients’ prognosis. (A) Expression of CCAT1 in four HCC cell lines and two liver normal cell lines. Data are presented as mean ± standard error based on at least three independent experiments. **p < 0.01, ***p < 0.001. (B) Differences in CCAT1 expression levels between HCC tissues and pair-matched noncancerous hepatic tissues. The expression of CCAT1 was normalized to that of 18S rRNA, which is an abundant and constitutively expressed non-coding RNA. Statistical differences between samples were analyzed using the Wilcoxon signed-rank test (n = 66, p < 0.001). (C, D) Kaplan–Meier analyses of correlations between the CCAT1 expression level and recurrence-free survival (C) or overall survival (D) of 66 HCC patients. The median expression level was used as the cut-off.

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