Figure 1From: Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge CCAT1 expression in HCC and its association with patients’ prognosis. (A) Expression of CCAT1 in four HCC cell lines and two liver normal cell lines. Data are presented as mean ± standard error based on at least three independent experiments. **p < 0.01, ***p < 0.001. (B) Differences in CCAT1 expression levels between HCC tissues and pair-matched noncancerous hepatic tissues. The expression of CCAT1 was normalized to that of 18S rRNA, which is an abundant and constitutively expressed non-coding RNA. Statistical differences between samples were analyzed using the Wilcoxon signed-rank test (n = 66, p < 0.001). (C, D) Kaplan–Meier analyses of correlations between the CCAT1 expression level and recurrence-free survival (C) or overall survival (D) of 66 HCC patients. The median expression level was used as the cut-off.Back to article page