Figure 3

Attenuated expression of CCAT1 inhibits the proliferation and migration of HCC cells. (A) The expression of CCAT1 in SMMC-7721 and HepG2 cells with CCAT1 stably repressed. (B) Repression of CCAT1 decreases the proliferation of SMMC-7721 and HepG2 cells. Cell number was determined by the CCK-8 assay, and the relative number of cells to 0 h is presented. (C) The colony number of CCAT1 repressed SMMC-7721 and HepG2 cells per well in 6-well plates. (D) Repression of CCAT1 decreased cell migration by transwell assays. All values are presented as mean ± standard error based on at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001.