Figure 6From: ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cellsExpression of cycle-related and apoptotic molecules in BP-CML cells with an ARE/SUZ12-regulated TK/GCV system. Bcl-2, Cycline D1, and Bax. CML blast crisis cells were transduced with Ad-S-TK, Ad-AS-TK, or empty adenovirus, and cultured in 100 μmol/l GCV for 48 h. Expression of Bcl-2, Cyclin D1, and Bax analyzed with Western blot (actin internal control).Back to article page