TY - JOUR AU - Siegel, R. AU - Ma, J. AU - Zou, Z. AU - Jemal, A. PY - 2014 DA - 2014// TI - Cancer statistics, 2014 JO - CA Cancer J Clin VL - 64 UR - https://doi.org/10.3322/caac.21208 DO - 10.3322/caac.21208 ID - Siegel2014 ER - TY - JOUR AU - Moore, M. J. AU - Goldstein, D. AU - Hamm, J. AU - Figer, A. AU - Hecht, J. R. AU - Gallinger, S. PY - 2007 DA - 2007// TI - Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group JO - J Clin Oncol VL - 25 UR - https://doi.org/10.1200/JCO.2006.07.9525 DO - 10.1200/JCO.2006.07.9525 ID - Moore2007 ER - TY - JOUR AU - Conroy, T. AU - Desseigne, F. AU - Ychou, M. AU - Bouche, O. AU - Guimbaud, R. AU - Becouarn, Y. PY - 2011 DA - 2011// TI - FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer JO - N Engl J Med VL - 364 UR - https://doi.org/10.1056/NEJMoa1011923 DO - 10.1056/NEJMoa1011923 ID - Conroy2011 ER - TY - JOUR AU - Hoff, D. D. AU - Ramanathan, R. K. AU - Borad, M. J. AU - Laheru, D. A. AU - Smith, L. S. AU - Wood, T. E. PY - 2011 DA - 2011// TI - Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial JO - J Clin Oncol VL - 29 UR - https://doi.org/10.1200/JCO.2011.36.5742 DO - 10.1200/JCO.2011.36.5742 ID - Hoff2011 ER - TY - JOUR AU - Ueno, H. AU - Ioka, T. AU - Ikeda, M. AU - Ohkawa, S. AU - Yanagimoto, H. AU - Boku, N. PY - 2013 DA - 2013// TI - Randomized phase III study of gemcitabine plus S-1, S-1 alone, or gemcitabine alone in patients with locally advanced and metastatic pancreatic cancer in Japan and Taiwan: GEST study JO - J Clin Oncol VL - 31 UR - https://doi.org/10.1200/JCO.2012.43.3680 DO - 10.1200/JCO.2012.43.3680 ID - Ueno2013 ER - TY - JOUR AU - Paulson, A. S. AU - Tran Cao, H. S. AU - Tempero, M. A. AU - Lowy, A. M. PY - 2013 DA - 2013// TI - Therapeutic advances in pancreatic cancer JO - Gastroenterology VL - 144 UR - https://doi.org/10.1053/j.gastro.2013.01.078 DO - 10.1053/j.gastro.2013.01.078 ID - Paulson2013 ER - TY - JOUR AU - Frese, K. K. AU - Neesse, A. AU - Cook, N. AU - Bapiro, T. E. AU - Lolkema, M. P. AU - Jodrell, D. I. PY - 2012 DA - 2012// TI - nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer JO - Cancer Discov VL - 2 UR - https://doi.org/10.1158/2159-8290.CD-11-0242 DO - 10.1158/2159-8290.CD-11-0242 ID - Frese2012 ER - TY - JOUR AU - Ferrone, C. R. AU - Kattan, M. W. AU - Tomlinson, J. S. AU - Thayer, S. P. AU - Brennan, M. F. AU - Warshaw, A. L. PY - 2005 DA - 2005// TI - Validation of a postresection pancreatic adenocarcinoma nomogram for disease-specific survival JO - J Clin Oncol VL - 23 UR - https://doi.org/10.1200/JCO.2005.01.8101 DO - 10.1200/JCO.2005.01.8101 ID - Ferrone2005 ER - TY - JOUR AU - Broeck, A. AU - Vankelecom, H. AU - Eijsden, R. AU - Govaere, O. AU - Topal, B. PY - 2012 DA - 2012// TI - Molecular markers associated with outcome and metastasis in human pancreatic cancer JO - J Exp Clin Cancer Res VL - 31 UR - https://doi.org/10.1186/1756-9966-31-68 DO - 10.1186/1756-9966-31-68 ID - Broeck2012 ER - TY - JOUR AU - Zheng, C. AU - Jia, W. AU - Tang, Y. AU - Zhao, H. AU - Jiang, Y. AU - Sun, S. PY - 2012 DA - 2012// TI - Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway JO - J Exp Clin Cancer Res VL - 31 UR - https://doi.org/10.1186/1756-9966-31-84 DO - 10.1186/1756-9966-31-84 ID - Zheng2012 ER - TY - JOUR AU - Ma, C. AU - Nong, K. AU - Wu, B. AU - Dong, B. AU - Bai, Y. AU - Zhu, H. PY - 2014 DA - 2014// TI - miR-212 promotes pancreatic cancer cell growth and invasion by targeting the hedgehog signaling pathway receptor patched-1 JO - J Exp Clin Cancer Res VL - 33 UR - https://doi.org/10.1186/1756-9966-33-54 DO - 10.1186/1756-9966-33-54 ID - Ma2014 ER - TY - JOUR AU - Takai, Y. AU - Miyoshi, J. AU - Ikeda, W. AU - Ogita, H. PY - 2008 DA - 2008// TI - Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation JO - Nat Rev Mol Cell Biol VL - 9 UR - https://doi.org/10.1038/nrm2457 DO - 10.1038/nrm2457 ID - Takai2008 ER - TY - JOUR AU - Takai, Y. AU - Ikeda, W. AU - Ogita, H. AU - Rikitake, Y. PY - 2008 DA - 2008// TI - The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin JO - Annu Rev Cell Dev Biol VL - 24 UR - https://doi.org/10.1146/annurev.cellbio.24.110707.175339 DO - 10.1146/annurev.cellbio.24.110707.175339 ID - Takai2008 ER - TY - JOUR AU - Rikitake, Y. AU - Mandai, K. AU - Takai, Y. PY - 2012 DA - 2012// TI - The role of nectins in different types of cell-cell adhesion JO - J Cell Sci VL - 125 UR - https://doi.org/10.1242/jcs.099572 DO - 10.1242/jcs.099572 ID - Rikitake2012 ER - TY - JOUR AU - Reymond, N. AU - Fabre, S. AU - Lecocq, E. AU - Adelaide, J. AU - Dubreuil, P. AU - Lopez, M. PY - 2001 DA - 2001// TI - Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M103810200 DO - 10.1074/jbc.M103810200 ID - Reymond2001 ER - TY - JOUR AU - Fabre, S. AU - Reymond, N. AU - Cocchi, F. AU - Menotti, L. AU - Dubreuil, P. AU - Campadelli-Fiume, G. PY - 2002 DA - 2002// TI - Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C’-C”-D beta-strands of the nectin1 V domain JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M203228200 DO - 10.1074/jbc.M203228200 ID - Fabre2002 ER - TY - JOUR AU - Athanassiadou, A. M. AU - Patsouris, E. AU - Tsipis, A. AU - Gonidi, M. AU - Athanassiadou, P. PY - 2011 DA - 2011// TI - The significance of Survivin and Nectin-4 expression in the prognosis of breast carcinoma JO - Folia Histochem Cytobiol VL - 49 UR - https://doi.org/10.5603/FHC.2011.0005 DO - 10.5603/FHC.2011.0005 ID - Athanassiadou2011 ER - TY - JOUR AU - Derycke, M. S. AU - Pambuccian, S. E. AU - Gilks, C. B. AU - Kalloger, S. E. AU - Ghidouche, A. AU - Lopez, M. PY - 2010 DA - 2010// TI - Nectin 4 overexpression in ovarian cancer tissues and serum: potential role as a serum biomarker JO - Am J Clin Pathol VL - 134 UR - https://doi.org/10.1309/AJCPGXK0FR4MHIHB DO - 10.1309/AJCPGXK0FR4MHIHB ID - Derycke2010 ER - TY - JOUR AU - Takano, A. AU - Ishikawa, N. AU - Nishino, R. AU - Masuda, K. AU - Yasui, W. AU - Inai, K. PY - 2009 DA - 2009// TI - Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer JO - Cancer Res VL - 69 UR - https://doi.org/10.1158/0008-5472.CAN-09-0016 DO - 10.1158/0008-5472.CAN-09-0016 ID - Takano2009 ER - TY - JOUR AU - Fabre-Lafay, S. AU - Monville, F. AU - Garrido-Urbani, S. AU - Berruyer-Pouyet, C. AU - Ginestier, C. AU - Reymond, N. PY - 2007 DA - 2007// TI - Nectin-4 is a new histological and serological tumor associated marker for breast cancer JO - BMC Cancer VL - 7 UR - https://doi.org/10.1186/1471-2407-7-73 DO - 10.1186/1471-2407-7-73 ID - Fabre-Lafay2007 ER - TY - JOUR AU - Pavlova, N. N. AU - Pallasch, C. AU - Elia, A. E. AU - Braun, C. J. AU - Westbrook, T. F. AU - Hemann, M. PY - 2013 DA - 2013// TI - A role for PVRL4-driven cell-cell interactions in tumorigenesis JO - Elife VL - 2 UR - https://doi.org/10.7554/eLife.00358 DO - 10.7554/eLife.00358 ID - Pavlova2013 ER - TY - JOUR AU - Kinugasa, M. AU - Amano, H. AU - Satomi-Kobayashi, S. AU - Nakayama, K. AU - Miyata, M. AU - Kubo, Y. PY - 2012 DA - 2012// TI - Necl-5/poliovirus receptor interacts with VEGFR2 and regulates VEGF-induced angiogenesis JO - Circ Res VL - 110 UR - https://doi.org/10.1161/CIRCRESAHA.111.256834 DO - 10.1161/CIRCRESAHA.111.256834 ID - Kinugasa2012 ER - TY - JOUR AU - Yu, X. AU - Harden, K. AU - Gonzalez, L. C. AU - Francesco, M. AU - Chiang, E. AU - Irving, B. PY - 2009 DA - 2009// TI - The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells JO - Nat Immunol VL - 10 UR - https://doi.org/10.1038/ni.1674 DO - 10.1038/ni.1674 ID - Yu2009 ER - TY - JOUR AU - Escalante, N. K. AU - Rossum, A. AU - Lee, M. AU - Choy, J. C. PY - 2011 DA - 2011// TI - CD155 on human vascular endothelial cells attenuates the acquisition of effector functions in CD8 T cells JO - Arterioscler Thromb Vasc Biol VL - 31 UR - https://doi.org/10.1161/ATVBAHA.111.224162 DO - 10.1161/ATVBAHA.111.224162 ID - Escalante2011 ER - TY - JOUR AU - Levin, S. D. AU - Taft, D. W. AU - Brandt, C. S. AU - Bucher, C. AU - Howard, E. D. AU - Chadwick, E. M. PY - 2011 DA - 2011// TI - Vstm3 is a member of the CD28 family and an important modulator of T-cell function JO - Eur J Immunol VL - 41 UR - https://doi.org/10.1002/eji.201041136 DO - 10.1002/eji.201041136 ID - Levin2011 ER - TY - JOUR AU - Stanietsky, N. AU - Rovis, T. L. AU - Glasner, A. AU - Seidel, E. AU - Tsukerman, P. AU - Yamin, R. PY - 2013 DA - 2013// TI - Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR JO - Eur J Immunol VL - 43 UR - https://doi.org/10.1002/eji.201243072 DO - 10.1002/eji.201243072 ID - Stanietsky2013 ER - TY - JOUR AU - Liu, J. AU - Qian, X. AU - Chen, Z. AU - Xu, X. AU - Gao, F. AU - Zhang, S. PY - 2012 DA - 2012// TI - Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226 JO - J Immunol VL - 188 UR - https://doi.org/10.4049/jimmunol.1200324 DO - 10.4049/jimmunol.1200324 ID - Liu2012 ER - TY - BOOK AU - Sobin, L. H. AU - Gospodarowicz, M. K. AU - Wittekind, C. PY - 2009 DA - 2009// TI - TNM Classification of Malignant Tumours PB - Wiley-Liss CY - New York ID - Sobin2009 ER - TY - JOUR AU - Yamato, I. AU - Sho, M. AU - Shimada, K. AU - Hotta, K. AU - Ueda, Y. AU - Yasuda, S. PY - 2012 DA - 2012// TI - PCA-1/ALKBH3 contributes to pancreatic cancer by supporting apoptotic resistance and angiogenesis JO - Cancer Res VL - 72 UR - https://doi.org/10.1158/0008-5472.CAN-12-0328 DO - 10.1158/0008-5472.CAN-12-0328 ID - Yamato2012 ER - TY - JOUR AU - Ikeda, N. AU - Adachi, M. AU - Taki, T. AU - Huang, C. AU - Hashida, H. AU - Takabayashi, A. PY - 1999 DA - 1999// TI - Prognostic significance of angiogenesis in human pancreatic cancer JO - Br J Cancer VL - 79 UR - https://doi.org/10.1038/sj.bjc.6690248 DO - 10.1038/sj.bjc.6690248 ID - Ikeda1999 ER - TY - JOUR AU - Migita, K. AU - Takayama, T. AU - Matsumoto, S. AU - Wakatsuki, K. AU - Tanaka, T. AU - Ito, M. PY - 2014 DA - 2014// TI - Prognostic impact of RING box protein-1 (RBX1) expression in gastric cancer JO - Gastric Cancer VL - 17 UR - https://doi.org/10.1007/s10120-013-0318-y DO - 10.1007/s10120-013-0318-y ID - Migita2014 ER - TY - JOUR AU - Chan, C. J. AU - Andrews, D. M. AU - Smyth, M. J. PY - 2012 DA - 2012// TI - Receptors that interact with nectin and nectin-like proteins in the immunosurveillance and immunotherapy of cancer JO - Curr Opin Immunol VL - 24 UR - https://doi.org/10.1016/j.coi.2012.01.009 DO - 10.1016/j.coi.2012.01.009 ID - Chan2012 ER - TY - JOUR AU - Fuchs, A. AU - Colonna, M. PY - 2006 DA - 2006// TI - The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance JO - Semin Cancer Biol VL - 16 UR - https://doi.org/10.1016/j.semcancer.2006.07.002 DO - 10.1016/j.semcancer.2006.07.002 ID - Fuchs2006 ER - TY - JOUR AU - Noyce, R. S. AU - Bondre, D. G. AU - Ha, M. N. AU - Lin, L. T. AU - Sisson, G. AU - Tsao, M. S. PY - 2011 DA - 2011// TI - Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus JO - PLoS Pathog VL - 7 UR - https://doi.org/10.1371/journal.ppat.1002240 DO - 10.1371/journal.ppat.1002240 ID - Noyce2011 ER - TY - JOUR AU - Folkman, J. PY - 1995 DA - 1995// TI - Angiogenesis in cancer, vascular, rheumatoid and other disease JO - Nat Med VL - 1 UR - https://doi.org/10.1038/nm0195-27 DO - 10.1038/nm0195-27 ID - Folkman1995 ER - TY - JOUR AU - Carmeliet, P. AU - Jain, R. K. PY - 2000 DA - 2000// TI - Angiogenesis in cancer and other diseases JO - Nature VL - 407 UR - https://doi.org/10.1038/35025220 DO - 10.1038/35025220 ID - Carmeliet2000 ER - TY - JOUR AU - Yasuda, S. AU - Sho, M. AU - Yamato, I. AU - Yoshiji, H. AU - Wakatsuki, K. AU - Nishiwada, S. PY - 2013 DA - 2013// TI - Simultaneous blockade of programmed death 1 and vascular endothelial growth factor receptor 2 (VEGFR2) induces synergistic anti-tumour effect in vivo JO - Clin Exp Immunol VL - 172 UR - https://doi.org/10.1111/cei.12069 DO - 10.1111/cei.12069 ID - Yasuda2013 ER - TY - JOUR AU - Fujito, T. AU - Ikeda, W. AU - Kakunaga, S. AU - Minami, Y. AU - Kajita, M. AU - Sakamoto, Y. PY - 2005 DA - 2005// TI - Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3 JO - J Cell Biol VL - 171 UR - https://doi.org/10.1083/jcb.200501090 DO - 10.1083/jcb.200501090 ID - Fujito2005 ER - TY - JOUR AU - Cho, Y. AU - Miyamoto, M. AU - Kato, K. AU - Fukunaga, A. AU - Shichinohe, T. AU - Kawarada, Y. PY - 2003 DA - 2003// TI - CD4+ and CD8+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma JO - Cancer Res VL - 63 ID - Cho2003 ER - TY - JOUR AU - Galon, J. AU - Costes, A. AU - Sanchez-Cabo, F. AU - Kirilovsky, A. AU - Mlecnik, B. AU - Lagorce-Pages, C. PY - 2006 DA - 2006// TI - Type, density, and location of immune cells within human colorectal tumors predict clinical outcome JO - Science VL - 313 UR - https://doi.org/10.1126/science.1129139 DO - 10.1126/science.1129139 ID - Galon2006 ER - TY - JOUR AU - Nomi, T. AU - Sho, M. AU - Akahori, T. AU - Hamada, K. AU - Kubo, A. AU - Kanehiro, H. PY - 2007 DA - 2007// TI - Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer JO - Clin Cancer Res VL - 13 UR - https://doi.org/10.1158/1078-0432.CCR-06-2746 DO - 10.1158/1078-0432.CCR-06-2746 ID - Nomi2007 ER - TY - JOUR AU - Lee, H. E. AU - Chae, S. W. AU - Lee, Y. J. AU - Kim, M. A. AU - Lee, H. S. AU - Lee, B. L. PY - 2008 DA - 2008// TI - Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer JO - Br J Cancer VL - 99 UR - https://doi.org/10.1038/sj.bjc.6604738 DO - 10.1038/sj.bjc.6604738 ID - Lee2008 ER - TY - JOUR AU - Enomoto, K. AU - Sho, M. AU - Wakatsuki, K. AU - Takayama, T. AU - Matsumoto, S. AU - Nakamura, S. PY - 2012 DA - 2012// TI - Prognostic importance of tumour-infiltrating memory T cells in oesophageal squamous cell carcinoma JO - Clin Exp Immunol VL - 168 UR - https://doi.org/10.1111/j.1365-2249.2012.04565.x DO - 10.1111/j.1365-2249.2012.04565.x ID - Enomoto2012 ER - TY - JOUR AU - Ino, Y. AU - Yamazaki-Itoh, R. AU - Shimada, K. AU - Iwasaki, M. AU - Kosuge, T. AU - Kanai, Y. PY - 2013 DA - 2013// TI - Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer JO - Br J Cancer VL - 108 UR - https://doi.org/10.1038/bjc.2013.32 DO - 10.1038/bjc.2013.32 ID - Ino2013 ER -