Figure 8

Expression of miR-223 was negatively correlated with FBXW7 in cells and tissues. (A) qRT-PCR detection of FBXW7 mRNA in 7901 and BGC-823 and their respective resistant cells; (B) qRT-PCR detection of FBXW7 mRNA in tumor and control tissues; (C) qRT-PCR detection of FBXW7 mRNA in different stages in tumor tissues; (D) A statistically significant inverse correlation between miR-223 and FBXW7 mRNA levels in 15 cases of GC tissues. (Spearman’s correlation analysis, r = −0.915, p = 0.000). Data are expressed as the mean ± S.D. of three individual experiments. Corresponding P values analyzed by Spearman correlation test are indicated.