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Table 2 Numerical and percentage distribution of ligand/VEGFR-2 and VEGFR-2/pVEGFR-2 co-expression in the tumor cells

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

  N0/M0 N+ M+
n (%) n (%) n (%)
Tumor center    
VEGF-C+/VEGFR-2+ 22/14 (64) 16/9 (56) 14/7 (50)
VEGF-D+/VEGFR-2+ 22/16 (73) 12/10 (83) 11/7 (64)
VEGFR-2+/pVEGFR-2Tyr1175+ 19/14 (74) 13/11 (85) 12/5 (42)
VEGFR-2+/pVEGFR-2Tyr1214+ 19/17 (89) 13/10 (77) 13/11 (85)
Tumor budding    
VEGF-C+/VEGFR-2+ 16/12 (75) 10/7 (70) 10/8 (80)
VEGF-D+/ VEGFR-2+ 16/13 (81) 10/8 (80) 13/8 (62)
VEGFR-2+/pVEGFR-2Tyr1175+ 16/11 (69) 10/8 (80) 12/7 (58)
VEGFR-2+/pVEGFR-2Tyr1214+ 16/16 (100) 10/9 (90) 13/13 (100)
  1. n: total number of ligand positive cases/total number of ligand positive cases with concomitant VEGFR-2 positivity or total number of VEGFR-2 positive cases/total number of VEGFR-2 positive cases with concomitant pVEGFR-2 positivity. There were no significant differences between the groups