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Table 2 Numerical and percentage distribution of ligand/VEGFR-2 and VEGFR-2/pVEGFR-2 co-expression in the tumor cells

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

 

N0/M0

N+

M+

n (%)

n (%)

n (%)

Tumor center

   

VEGF-C+/VEGFR-2+

22/14 (64)

16/9 (56)

14/7 (50)

VEGF-D+/VEGFR-2+

22/16 (73)

12/10 (83)

11/7 (64)

VEGFR-2+/pVEGFR-2Tyr1175+

19/14 (74)

13/11 (85)

12/5 (42)

VEGFR-2+/pVEGFR-2Tyr1214+

19/17 (89)

13/10 (77)

13/11 (85)

Tumor budding

   

VEGF-C+/VEGFR-2+

16/12 (75)

10/7 (70)

10/8 (80)

VEGF-D+/ VEGFR-2+

16/13 (81)

10/8 (80)

13/8 (62)

VEGFR-2+/pVEGFR-2Tyr1175+

16/11 (69)

10/8 (80)

12/7 (58)

VEGFR-2+/pVEGFR-2Tyr1214+

16/16 (100)

10/9 (90)

13/13 (100)

  1. n: total number of ligand positive cases/total number of ligand positive cases with concomitant VEGFR-2 positivity or total number of VEGFR-2 positive cases/total number of VEGFR-2 positive cases with concomitant pVEGFR-2 positivity. There were no significant differences between the groups
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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