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Table 3 Numerical distribution and statistical significance of ligand/VEGFR-2 correlations in tumor cells of CC tissue

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

VEGFR-2

VEGF-C

p-value

VEGF-D

p-value

+

-

(r)

+

-

(r)

Tumor center

+

30

22

NS

33

12

0.0001

-

11

16

 

12

27

(0.425)

Tumor budding

+

27

9

NS

29

10

0.0002

-

20

10

 

10

21

(0.421)

  1. Positive tumoral expression of VEGFR-2 is positively correlated with positive tumoral VEGF-D expression in tumor center and tumor budding regions. r = Spearman rank correlation coefficient. p < 0.05 was taken as statistically significant. NS, not significant