| |
Score
|
N0/M0
|
N+
|
M+
|
CC
|
|---|
| |
%
|
%
|
%
|
%
|
|---|
|
Tumor center
|
|
VEGFR-2
|
0
|
47
|
46
|
46
|
46
|
|
1
|
39
|
46
|
50
|
54
|
|
2
|
14
|
8
|
4
|
|
Cytoplasmatic VEGFR-2Tyr1175
|
0
|
36
|
29
|
43
|
36
|
|
1
|
14
|
17
|
14
|
64
|
|
2
|
50
|
54
|
43
|
|
Nuclear VEGFR-2Tyr1175
|
-
|
6
|
4
|
4
|
5
|
|
+
|
94
|
96
|
96
|
95
|
|
Cytoplasmatic VEGFR-2Tyr1214
|
0
|
26
|
26
|
8
|
20
|
|
1
|
31
|
26
|
29
|
80
|
|
2
|
43
|
48
|
63
|
|
Nuclear VEGFR-2Tyr1214
|
-
|
31
|
26
|
50
|
36
|
| |
+
|
69
|
74
|
50
|
64
|
|
Tumor budding
|
|
VEGFR-2
|
0
|
41
|
50
|
43
|
45
|
|
1
|
48
|
10
|
43
|
55
|
|
2
|
11
|
40
|
14
|
|
Cytoplasmatic VEGFR-2Tyr1175
|
0
|
33
|
30
|
36
|
33
|
|
1
|
15
|
5
|
14
|
67
|
|
2
|
52
|
65
|
50
|
|
Nuclear VEGFR-2Tyr1175
|
-
|
4
|
5
|
0
|
3
|
|
+
|
96
|
95
|
100
|
97
|
|
Cytoplasmatic VEGFR-2Tyr1214
|
0
|
11
|
21
|
0
|
11
|
|
1
|
22
|
26
|
17
|
89
|
|
2
|
67
|
53
|
83
|
|
Nuclear VEGFR-2Tyr1214
|
-
|
36
|
21
|
61
|
38
|
|
+
|
67
|
79
|
39
|
62
|
- The intensity of the tumoral staining was scored on a semiquantitative scale from 0 to 2 for the investigated biomolecule (0: no staining, 1: weak staining, 2: strong staining). For the statistical analysis using Fisher’s exact test the examined cases were separated into two groups characterized by a negative/positive expression for VEGFR-2, VEGFR-2Tyr1175 and VEGFR-2Tyr1214. The line in the staining intensity column indicates this dichotomization for each biomolecule. There were no significant differences between the groups
