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Table 7 Numerical and percentage distribution of ligand/VEGFR-2 and VEGFR-2/pVEGFR-2 co-expression in the vasculature

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

  N0/M0 N+ M+
n (%) n (%) n (%)
VEGF-C+/VEGFR-2+    
Capillaries zone 1 20/8 (40) 9/6 (67) 9/6 (67)
zone 2 16/16 (100) 11/11 (100) 11/9 (82)
zone 3 18/11 (61) 13/11 (85) 16/14 (88)
Small vessels zone 1 16/12 (75) 11/6 (55) 15/8 (53)
zone 2 23/21 (91) 16/15 (94) 17/14 (82)
zone 3 17/9 (53) 14/8 (57) 13/7 (54)
VEGF-D+/VEGFR-2+    
Capillaries zone 1 11/10 (91) 8/7 (88) 9/8 (89)
zone 2 19/19 (100) 11/11 (100) 15/14 (93)
zone 3 21/15 (71) 14/12 (86) 12/12 (100)
Small vessels zone 1 10/9 (90) 6/4 (67) 8/5 (63)
zone 2 27/24 (89) 17/16 (94) 19/17 (89)
zone 3 26/16 (62) 19/11 (58) 15/10 (67)
VEGFR-2+/VEGFR-2 Tyr1175 +    
Capillaries zone 1 20/17 (85) 14/14 (100) 12/10 (83)
zone 2 34/31 (91) 21/19 (90) 18/15 (83)
zone 3 22/22 (100) 18/17 (94) 19/18 (95)
Small vessels zone 1 13/10 (77) 8/8 (100) 11/9 (82)
zone 2 29/26 (90) 20/18 (90) 16/14 (88)
zone 3 18/16 (89) 12/12 (100) 9/8 (89)
VEGFR-2+/VEGFR-2 Tyr1214 +    
Capillaries zone 1 19/18 (95) 13/10 (77) 14/13 (93)
zone 2 33/32 (97) 21/19 (90) 21/21 (100)
zone 3 21/21 (100) 15/15 (100) 21/21 (100)
Small vessels zone 1 15/14 (93) 8/6 (75) 11/10 (91)
zone 2 27/27 (100) 20/19 (95) 19/19 (100)
zone 3 17/17 (100) 12/11 (92) 12/12 (100)
  1. n: total number of ligand positive cases / total number of ligand positive cases with concomitant VEGFR-2 positivity or total number of VEGFR-2 positive cases / total number of VEGFR-2 positive cases with concomitant pVEGFR-2 positivity. There were no significant differences between the groups