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Table 8 Numerical distribution and statistical significance of VEGF-D/VEGFR-2 and VEGFR-2/pVEGFR-2Tyr1214 correlations in the vasculature of CC tissue

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

VEGFR-2

VEGF-D

p-value

VEGFR-2Tyr1214

p-value

+/−

+

-

(r)

+

-

(r)

Ca zone 1

25

3

0.0001

41

5

0.0001

23

32

(0.454)

18

16

(0.406)

Ca zone 2

44

1

0.014

72

3

0.0001

32

7

(0.267)

3

4

(0.531)

Ca zone 3

39

8

0.025

57

1

0.001

21

14

(0.256)

17

5

(0.356)

SV zone 1

18

6

0.013

40

4

0.0001

17

20

(0.313)

12

14

(0.494)

SV zone 2

57

6

0.034

65

1

0.0001

11

5

(0.236)

6

4

(0.524)

SV zone 3

37

23

NS

40

1

NS

6

7

25

4

  1. Positive vascular expression of VEGFR-2 is positively correlated with positive vascular VEGF-D expression and positive vascular VEGFR-2Tyr1214 expression in capillaries and small vessels in zone 1 and 2 and capillaries in zone 3. r = Spearman rank correlation coefficient. p < 0.05 was taken as statistically significant. NS, not significant. Ca = capillaries; SV = small vessels