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Table 8 Numerical distribution and statistical significance of VEGF-D/VEGFR-2 and VEGFR-2/pVEGFR-2Tyr1214 correlations in the vasculature of CC tissue

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

VEGFR-2 VEGF-D p-value VEGFR-2Tyr1214 p-value
+/− + - (r) + - (r)
Ca zone 1 25 3 0.0001 41 5 0.0001
23 32 (0.454) 18 16 (0.406)
Ca zone 2 44 1 0.014 72 3 0.0001
32 7 (0.267) 3 4 (0.531)
Ca zone 3 39 8 0.025 57 1 0.001
21 14 (0.256) 17 5 (0.356)
SV zone 1 18 6 0.013 40 4 0.0001
17 20 (0.313) 12 14 (0.494)
SV zone 2 57 6 0.034 65 1 0.0001
11 5 (0.236) 6 4 (0.524)
SV zone 3 37 23 NS 40 1 NS
6 7 25 4
  1. Positive vascular expression of VEGFR-2 is positively correlated with positive vascular VEGF-D expression and positive vascular VEGFR-2Tyr1214 expression in capillaries and small vessels in zone 1 and 2 and capillaries in zone 3. r = Spearman rank correlation coefficient. p < 0.05 was taken as statistically significant. NS, not significant. Ca = capillaries; SV = small vessels