Table 4 Univariate and multivariate survival analysis of overall survival

Sex (female vs male)

0.5873

Age (≤70 y vs >70y)

0.0962

TNM stage

0.0000*

0.000*

8.19

3.5370-19.0053

Lymph nodes (+ vs -)

0.0000*

Metastasis (+ vs–)

0.0000*

CC3 (high expression vs otherwise)

0.0006*

0.998

1.00

0.3627-2.7655

HMGB1 (high expression vs otherwise)

0.0281*

0.008*

3.55

1.3972-9.0147

RAGE (high expression vs otherwise)

0.3119

Ki67 (high expression vs otherwise)

0.0330*

0.347

1.50

0.6451-3.4806