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Table 1 Association between clinicopathological features and DPPA4 or Ki-67 protein expression

From: Developmental pluripotency-associated 4: a novel predictor for prognosis and a potential therapeutic target for colon cancer

  n DPPA4 expression P value
Negative (n = 62) (%) Weak (n = 54) (%) Strong (n = 69) (%)
Age, years (n,%)      0.423
<65 72 21 (33.9) 20 (37.0) 31 (44.9)  
≥65 113 41 (66.1) 34 (63.0) 38 (55.1)  
Gender (n,%)      0.519
Male 79 30 (48.4) 22 (40.7) 27 (39.1)  
Female 106 32 (51.6) 32 (59.3) 42 (60.9)  
Location (n,%)      0.650
Right 74 26 (41.9) 19 (35.2) 29 (42.0)  
Transverse 18 7 (11.3) 6 (11.1) 5 (7.2)  
Left 19 3 (4.8) 7 (13.0) 9 (13.0)  
Sigmoid colon 74 26 (41.9) 22 (40.7) 26 (37.7)  
T stage (n,%)      0.028*
T1 7 2 (3.2) 3 (5.6) 2 (2.9)  
T2 21 10 (16.1) 7 (13.0) 4 (5.8)  
T3 72 29 (46.8) 23 (42.6) 20 (29.0)  
T4 85 21 (33.9) 21 (38.9) 43 (62.3)  
N stage (n,%)      0.012*
N0 96 42 (67.7) 26 (48.1) 28 (40.6)  
N1 58 16 (25.8) 18 (33.3) 24 (34.8)  
N2 31 4 (6.5) 10 (18.5) 17 (24.6)  
M stage (n,%)      0.003*
M0 168 60 (96.8) 52 (96.3) 56 (81.2)  
M1 17 2 (3.2) 2 (3.7) 13 (18.8)  
AJCC stage (n,%)      0.010*
I 22 11 (17.7) 6 (11.1) 5 (7.2)  
II 71 29 (46.8) 20 (37.0) 22 (31.9)  
III 75 20 (32.3) 26 (48.1) 29 (42.0)  
IV 17 2 (3.2) 2 (3.7) 13 (18.8)  
Differentiation (n, %)      0.002*
High 90 41 (66.1) 27 (50.0) 22 (31.9)  
Moderate 68 17 (27.4) 20 (37.0) 31 (44.9)  
Low 27 4 (6.5) 7 (13.0) 16 (23.2)  
Vascular invasion (n, %)      0.420
Yes 173 60 (96.8) 50 (92.6) 63 (91.3)  
No 12 2 (3.2) 4 (7.4) 6 (8.7)  
Ki-67 index (n, %)      0.071
Negative 36 13 (21.0) 15 (27.8) 8 (11.6)  
Positive 149 49 (79.0) 39 (72.2) 61 (88.4)  
  1. *P < 0.05 indicates a significant association among the variables