Table 1 Association between clinicopathological features and DPPA4 or Ki-67 protein expression

Age, years (n,%)

0.423

<65

72

21 (33.9)

20 (37.0)

31 (44.9)

≥65

113

41 (66.1)

34 (63.0)

38 (55.1)

Gender (n,%)

0.519

Male

79

30 (48.4)

22 (40.7)

27 (39.1)

Female

106

32 (51.6)

32 (59.3)

42 (60.9)

Location (n,%)

0.650

Right

74

26 (41.9)

19 (35.2)

29 (42.0)

Transverse

18

7 (11.3)

6 (11.1)

5 (7.2)

Left

19

3 (4.8)

7 (13.0)

9 (13.0)

Sigmoid colon

74

26 (41.9)

22 (40.7)

26 (37.7)

T stage (n,%)

0.028*

T1

7

2 (3.2)

3 (5.6)

2 (2.9)

T2

21

10 (16.1)

7 (13.0)

4 (5.8)

T3

72

29 (46.8)

23 (42.6)

20 (29.0)

T4

85

21 (33.9)

21 (38.9)

43 (62.3)

N stage (n,%)

0.012*

N0

96

42 (67.7)

26 (48.1)

28 (40.6)

N1

58

16 (25.8)

18 (33.3)

24 (34.8)

N2

31

4 (6.5)

10 (18.5)

17 (24.6)

M stage (n,%)

0.003*

M0

168

60 (96.8)

52 (96.3)

56 (81.2)

M1

17

2 (3.2)

2 (3.7)

13 (18.8)

AJCC stage (n,%)

0.010*

I

22

11 (17.7)

6 (11.1)

5 (7.2)

II

71

29 (46.8)

20 (37.0)

22 (31.9)

III

75

20 (32.3)

26 (48.1)

29 (42.0)

IV

17

2 (3.2)

2 (3.7)

13 (18.8)

Differentiation (n, %)

0.002*

High

90

41 (66.1)

27 (50.0)

22 (31.9)

Moderate

68

17 (27.4)

20 (37.0)

31 (44.9)

Low

27

4 (6.5)

7 (13.0)

16 (23.2)

Vascular invasion (n, %)

0.420

Yes

173

60 (96.8)

50 (92.6)

63 (91.3)

No

12

2 (3.2)

4 (7.4)

6 (8.7)

Ki-67 index (n, %)

0.071

Negative

36

13 (21.0)

15 (27.8)

8 (11.6)

Positive

149

49 (79.0)

39 (72.2)

61 (88.4)