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Table 2 Univariate Cox proportional hazards model for overall survival (OS) and disease-free survival (DFS)

From: Developmental pluripotency-associated 4: a novel predictor for prognosis and a potential therapeutic target for colon cancer

  DFS OS
  HR 95 % CI P-value HR 95 % CI P-value
Age, years       
<65     
≥65 1.100 0.660–1.834 0.714 0.934 0.530–1.644 0.812
Gender       
Male       
Female 1.013 0.617–1.662 0.960 1.546 0.860–2.776 0.145
Tumor location       
Right     
Transverse 0.816 0.309–2.155 0.681 0.789 0.267–2.334 0.669
Left 1.392 0.619–3.130 0.423 1.291 0.512–3.252 0.589
Sigmoid colon 1.250 0.718–2.176 0.431 1.145 0.614–2.135 0.671
T stage       
T1 0.494 0.119–2.049 0.331 0.988 0.299–3.259 0.984
T2 0.203 0.063–0.660 0.008* 0.394 0.138–1.130 0.083
T3 0.484 0.284–0.827 0.008* 0.520 0.280–0.966 0.039*
T4     
N stage       
N0     
N1 5.887 3.025–11.456 <0.001* 4.157 2.009–8.602 <0.001*
N2 15.914 7.781–32.545 <0.001* 13.193 6.149–28.307 <0.001*
AJCC stage       
I     
II 1.108 0.305–4.027 0.877 0.667 0.201–2.215 0.508
III 6.823 2.097–22.199 0.001* 3.401 1.184–9.771 0.023*
IV 49.185 12.615–191.764 <0.001* 40.074 11.257–142.668 <0.001*
Differentiation       
High     
Moderate 1.315 0.750–2.306 0.340 1.458 0.764–2.780 0.253
Low 3.577 1.885–6.786 <0.001* 4.358 2.140–8.872 <0.001*
Vascular invasion       
Yes 4.900 2.469–9.721 <0.001* 4.638 2.152–9.997 <0.001*
No     
Ki-67 index       
Negative     
Weak 1.931 0.748–4.985 0.174 0.794 0.308–2.051 0.634
Positive 2.667 1.203–5.913 0.016* 1.175 0.592–2.335 0.645
DPPA4 expression       
Negative     
Weak 2.598 1.194–5.653 0.016* 2.117 0.862–5.196 0.102
Positive 6.118 3.004–12.462 <0.001* 6.348 2.875–14.014 <0.001*
  1. *P < 0.05 indicates a significant association among the variables