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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: YY1 regulates melanoma tumorigenesis through a miR-9 ~ RYBP axis

Fig. 6

Knock-down of RYBP inhibits melanoma cell proliferation, migration and invasion. (a) RYBP level was detected in WM1791C cells after treatment with si-RYBP (25 nM) or si-control (25 nM) by RT-qPCR; (b) Cell proliferation assay of WM1791C cells after treatment with si-RYBP or si-control by using CCK-8; (c) Cell cycle analysis by propidium iodide (PI) staining of WM1791C cells after treatment with si-RYBP or si-control l; (d) Wound healing assays of WM1791C cells after treatment with si-RYBP or si-control, The relative ratio of wound closure per field was shown in the right; (e) Transwell analysis of WM1791C cells after treatment with si-RYBP or si-control The relative ratio of invasive cells per field was shown below. For the quantitative results, the data are presented as the mean ± SEM, and the error bars represent the standard deviation obtained from three independent experiments. *, p < 0.05; **, p < 0.01

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