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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth

Fig. 5

Pathway scores from network enrichment analysis for DEG lists compiled of genes most differing by mRNA expression level between low and high inhibitory cell lines in vitro (Wh1 vs. Cr9) and ex vivo (PrNFB1 vs. PrTFB2). The network analysis (see “Network enrichment analysis” in Methods) was performed on 300 genes with highest fold change between each pair of cell lines. Horizontal and vertical grey lines denote levels of significance in NEA as false discovery rate = 0.01. Red line displays the linear fit. The text labels are given for pathways with NEA FDR < 0.001 in the both conditions

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