Fig. 2

Kaplan-Meier analyses of overall survivals after surgical removal of non-metastatic and metastatic clear cell renal cell carcinoma. piRNAs were dichotomized using their values (given in normalized units) obtained in the ROC analysis at the point of maximal accuracy to discriminate between dead and alive. The curves from 76 non-metastatic and 30 metastatic patients listed in Table 1 are presented according to (a) pathological stage, (b) grading, and expression of (c) piR-30924, (d) piR-57125, (e) piR-38756, and (f) combination of all three piRNAs. The log-rank test was used to confirm significant differences between the survival probabilities