From: Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas
Characteristics | Primary ccRCC, non-metastatica N = 76 | Primary ccRCC, metastatica N = 30 | P valueb |
---|---|---|---|
Age, median years (range) | 65 (37–87) | 61 (43–76) | 0.153 |
Sex, n (%) | |||
 Male | 58 (76) | 21 (70) | 0.621 |
 Female | 18 (24) | 9 (30) |  |
Pathological stage, n (%) | |||
 pT1 | 48 (63) | 5 (17) | <0.0001 |
 pT2 | 2 (3) | 1 (3) |  |
 pT3 | 25 (33) | 21 (70) |  |
 pT4 | 1 (1) | 3 (10) |  |
Fuhrman grade, n (%) | |||
 G1 | 11 (14) | 0 (0) | <0.0001 |
 G2 | 60 (79) | 11 (37) |  |
 G3 | 3 (4) | 16 (53) |  |
 G4 | 2 (3) | 3 (10) |  |
Surgical margins, n (%) | |||
 R0 | 71 (93) | 21 (70) | 0.003 |
 R1/2 | 5 (7) | 9 (30) |  |
Tumor size, median mm (range) | 48 (20–180) | 85 (35–170) | <0.0001 |
Patients followed,c n (%) | 76 (100) | 30 (100) | <0.0001 |
 Metastasis at follow-up | 17 (29) |  |  |
 Death at follow-up | 12 (16) | 25 (83) |  |
Follow-up, median month (range) | |||
 Overall | 65.7 (1.0–121) | 9.5 (1.2–65.2) | <0.0001 |
 No recurrence | 69.9 (5.3–121) |  |  |
 Recurrence | 30.4 (1.0–116) |  |  |