Table 1 Cohort characteristics, N = 106
From: Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas
| Characteristics | Primary ccRCC, non-metastatica N = 76 | Primary ccRCC, metastatica N = 30 | P valueb |
|---|---|---|---|
| Age, median years (range) | 65 (37–87) | 61 (43–76) | 0.153 |
| Sex, n (%) | |||
| Male | 58 (76) | 21 (70) | 0.621 |
| Female | 18 (24) | 9 (30) | |
| Pathological stage, n (%) | |||
| pT1 | 48 (63) | 5 (17) | <0.0001 |
| pT2 | 2 (3) | 1 (3) | |
| pT3 | 25 (33) | 21 (70) | |
| pT4 | 1 (1) | 3 (10) | |
| Fuhrman grade, n (%) | |||
| G1 | 11 (14) | 0 (0) | <0.0001 |
| G2 | 60 (79) | 11 (37) | |
| G3 | 3 (4) | 16 (53) | |
| G4 | 2 (3) | 3 (10) | |
| Surgical margins, n (%) | |||
| R0 | 71 (93) | 21 (70) | 0.003 |
| R1/2 | 5 (7) | 9 (30) | |
| Tumor size, median mm (range) | 48 (20–180) | 85 (35–170) | <0.0001 |
| Patients followed,c n (%) | 76 (100) | 30 (100) | <0.0001 |
| Metastasis at follow-up | 17 (29) | ||
| Death at follow-up | 12 (16) | 25 (83) | |
| Follow-up, median month (range) | |||
| Overall | 65.7 (1.0–121) | 9.5 (1.2–65.2) | <0.0001 |
| No recurrence | 69.9 (5.3–121) | ||
| Recurrence | 30.4 (1.0–116) | ||