Fig. 2

Gene expression of angiogenic factors is down-modulated by halofuginone. a, b NB4 cells were treated with 50, 100 or 200 ng/mL of HF for 6 hours and mRNA expression of angiogenesis determinants was assessed by PCR array. Graphic shows genes with greater differential expression compared to nontreated cells (Fold change = 1). Data are representative of two independent experiments (error bars, s.e.m.)